Endodontic treatment is primarily a combination of chemical as well as mechanical preparation of canal space which helps in the placement of a biocompatible material. The main purpose of endodontic treatment is to eradicate microorganisms from the infected root canal system and prevent recontamination. The principle constituents of an endodontic filling are core material "Gutta Percha" and "Endodontic Sealers." Endodontic sealers should ideally eliminate residual bacteria and prevent reinfection after chemomechanical treatment and obturation of the root canal. The aim of this study is to investigate the antimicrobial effect of four endodontic sealers against bacteria in biofilms commonly detected from persistent and secondary endodontic infections.
Keywords: Antibacterial activity; bacteria; biofilm; endodontic sealer.
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