Tumor Immune Microenvironment as a New Therapeutic Target for Hepatocellular Carcinoma Development

Dev Reprod. 2023 Dec;27(4):167-174. doi: 10.12717/DR.2023.27.4.167. Epub 2023 Dec 31.

Abstract

Development of hepatocellular carcinoma (HCC) is driven by a multistep and long-term process. Because current therapeutic strategies are limited for HCC patients, there are increasing demands for understanding of immunotherapy, which has made technological and conceptual innovations in the treatment of cancer. Here, I discuss HCC immunotherapy in the view of interaction between liver resident cells and immune cells.

Keywords: Hepatic immune cells; Hepatocellular carcinoma; Liver resident cells; Tumor immune microenvironment.