Remarkable Recovery in a Patient with Lethal Dose Paraquat Poisoning: A Case Report

JNMA J Nepal Med Assoc. 2023 Sep 1;61(265):738-740. doi: 10.31729/jnma.8263.

Abstract

Paraquat emerges as a formidable medical dilemma in Southeast Asia, its toxic effects attributed to the generation of free radicals and oxidative stress, with a specific predilection for diverse tissues, most notably the lungs. The scarcity of effective treatment modalities in resource-constrained settings magnifies the magnitude of the paraquat poisoning predicament. This report outlines the successful management of a 25-year-old man who ingested a lethal dose of paraquat. The patient presented solely with dysphagia devoid of accompanying symptoms, regardless of ingesting a fatal quantity of paraquat. The diagnosis was made based on history and a thorough clinical examination. Early, aggressive treatment with pulse therapy of steroids and antioxidants led to unexpected and quirky recovery. The case stresses the importance of prompt management and highlights the need for more research and public education to prevent future cases.

Keywords: antioxidants; case reports; corrosive; paraquat; steroids.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Lung
  • Male
  • Paraquat*
  • Poisoning*
  • Steroids
  • Treatment Outcome

Substances

  • Paraquat
  • Steroids