The Real Crisis in Antimicrobial Resistance: Failure to Anticipate and Respond

Clin Infect Dis. 2024 Jan 30:ciad758. doi: 10.1093/cid/ciad758. Online ahead of print.

Robert A Bonomo^{1

2

3

4}, Federico Perez⁵, Andrea M Hujer^{2

5}, Kristine M Hujer^{2

5}, Alejandro J Vila^{6

7}

¹ Clinician Scientist Investigator, Louis Stokes Cleveland Department of Veterans Affairs Medical Center (VAMC), Cleveland, Ohio, USA.
² Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
³ Departments of Pharmacology, Molecular Biology and Microbiology, Biochemistry, and Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
⁴ Case Western Reserve University (CWRU)-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA.
⁵ Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
⁶ Instituto de Biología Molecular y Celular de Rosario (IBR, CONICET-UNR), Rosario, Argentina.
⁷ Área Biofísica, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina.

No abstract available

Keywords: antibiotic resistance; β-lactam; β-lactamase inhibitor.