Patient reported outcomes after multivisceral resection for advanced rectal cancers in female patients

J Surg Oncol. 2024 May;129(6):1106-1112. doi: 10.1002/jso.27596. Epub 2024 Jan 30.

Abstract

Introduction: Multivisceral resections for rectal cancer can lead to long-term functional disturbances. This study aims to evaluate the quality-of-life outcomes in female patients who underwent multivisceral resection for rectal cancer, specifically focusing on urinary and sexual functions.

Methods: A cross-sectional study was conducted on female patients who underwent multivisceral rectal resections. Quality of life was assessed using the EORTC QLQ-CR29.

Results: Out of 198 female patients that underwent multivisceral resections, 69 were assessable for functional outcomes. The uterus was removed in 42 patients (61%), and the posterior vaginal wall in 34 (49%). A vaginal reconstructive procedure was carried out in 30% (21 patients). Patients reported the most troubles with urinary frequency (mean: 69.6; SD: 9.9), hair loss (mean: 64.7; SD: 13.9), pain during intercourse (mean: 44; SD: 40.7), and bowel frequency (mean: 36.9; SD: -10.7) in this order. Amongst the functional scales, anxiety about future health (mean: 42.5; SD: -018.9) and interest in sex (mean: 57.2; SD: 33.2) scored the lowest.

Conclusion: Multivisceral rectal resections in female patients are associated with physical and psychosocial changes resulting in urinary and bowel complaints, anxiety about future health, poor sexual health, and pain.

Keywords: functional outcomes; multivisceral resections; patient‐reported outcomes; rectal cancer.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Patient Reported Outcome Measures*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Proctectomy / adverse effects
  • Proctectomy / methods
  • Quality of Life*
  • Rectal Neoplasms* / pathology
  • Rectal Neoplasms* / surgery
  • Sexual Dysfunction, Physiological / etiology