Unusual Manifestation of Dermatomyositis: Exacerbation of Hypertriglyceridemia

Cureus. 2023 Dec 27;15(12):e51149. doi: 10.7759/cureus.51149. eCollection 2023 Dec.

Abstract

Systemic lupus erythematosus is known to cause autoimmune hyperlipidemia. We present a case in which hypertriglyceridemia was exacerbated by dermatomyositis. A 53-year-old woman with a medical history of undertreated hypertriglyceridemia complained of dyspnea and arthralgia. Despite the treatment, her triglyceride levels increased concurrently with the onset of arthralgia. She had characteristic skin manifestations and tested positive for anti-Jo-1 autoantibodies, leading to a diagnosis of dermatomyositis. Chronic inflammation may result in elevated triglyceride levels. When dermatomyositis is diagnosed, evaluating lipid abnormalities is important.

Keywords: anti-lipoprotein lipase antibody; autoimmune hypertriglyceridemia; collagen disease; dermatomyositis; hypertriglyceridemia (htg); inflammation; lipoprotein lipase; systemic lupus erythematosus.

Publication types

  • Case Reports