Superficial CD34-Positive Fibroblastic Tumor

Raul Perret; Isabelle Hostein

doi:10.1016/j.path.2023.06.001

Superficial CD34-Positive Fibroblastic Tumor

Surg Pathol Clin. 2024 Mar;17(1):1-12. doi: 10.1016/j.path.2023.06.001. Epub 2023 Aug 1.

Authors

Raul Perret¹, Isabelle Hostein²

Affiliations

¹ Department of Biopathology, Institut Bergonié, Comprehensive Cancer Center, Bordeaux F-33000, France. Electronic address: r.perret@bordeaux.unicancer.fr.
² Department of Biopathology, Institut Bergonié, Comprehensive Cancer Center, Bordeaux F-33000, France.

PMID: 38278599
DOI: 10.1016/j.path.2023.06.001

Abstract

Superficial CD34-positive fibroblastic tumor is a mesenchymal neoplasm of "intermediate malignancy" recently included in the fifth edition of the World Health Organization classification of soft tissue and bone tumors. In this review, we summarize the current knowledge on this rare entity with a special focus on its clinicopathological features, morphologic spectrum, and differential diagnosis. We also provide data regarding recent discoveries on its molecular profile and discuss its prognosis and management.

Keywords: PRDM10; Sarcoma; Superficial CD34-Positive fibroblastic tumor.

Publication types

Review

MeSH terms

Antigens, CD34
Biomarkers, Tumor
Diagnosis, Differential
Humans
Neoplasms, Connective and Soft Tissue* / diagnosis
Soft Tissue Neoplasms* / diagnosis
Soft Tissue Neoplasms* / pathology

Substances

Antigens, CD34
Biomarkers, Tumor