The power of weak, transient interactions across biology: A paradigm of emergent behavior

Physica D. 2023 Nov 15:454:133866. doi: 10.1016/j.physd.2023.133866. Epub 2023 Aug 4.

Abstract

A growing list of diverse biological systems and their equally diverse functionalities provides realizations of a paradigm of emergent behavior. In each of these biological systems, pervasive ensembles of weak, short-lived, spatially local interactions act autonomously to convey functionalities at larger spatial and temporal scales. In this article, a range of diverse systems and functionalities are presented in a cursory manner with literature citations for further details. Then two systems and their properties are discussed in more detail: yeast chromosome biology and human respiratory mucus.

Keywords: Biological paradigm; Emergent behavior; Transient interactions; Weak.