Significantly Higher 68 Ga-FAPI Than 18 F-FDG Uptake by Hidradenocarcinoma of Head and Neck on PET/CT

Clin Nucl Med. 2024 May 1;49(5):466-467. doi: 10.1097/RLU.0000000000005060. Epub 2024 Jan 24.

Abstract

Hidradenocarcinoma is quite rare in clinical practice. Herein, we describe the 68 Ga-FAPI and 18 F-FDG PET/CT findings of hidradenocarcinoma of the head and neck in a 75-year-old man. In the present case, the primary tumor and secondary lesions showed intense accumulation of 68 Ga-FAPI but only slight 18 F-FDG uptake. This case demonstrates that 68 Ga-FAPI PET/CT might be used as a helpful tool for evaluating hidradenocarcinoma.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Clear Cell*
  • Aged
  • Biological Transport
  • Fluorodeoxyglucose F18
  • Gallium Radioisotopes
  • Humans
  • Male
  • Neck / diagnostic imaging
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography
  • Sweat Gland Neoplasms* / diagnostic imaging

Substances

  • Fluorodeoxyglucose F18
  • Gallium-68
  • Gallium Radioisotopes