Prescribing of antivirals for COVID-19 in a South Australian local health network according to statewide guidelines

Intern Med J. 2024 Jan;54(1):183-186. doi: 10.1111/imj.16254.

Abstract

Antiviral drugs were rapidly implemented into clinical practice for the treatment of high-risk patients with COVID-19, prompting the development of statewide guidelines. This South-Australian study reviewed guideline adherence, assessed prescribing patterns and highlighted the inappropriate management of relative drug-drug interactions and dosing for renal function. Additionally, it evaluated the impact of inappropriate antiviral drug use and suggested methods to improve quality use of medicines.

Keywords: COVID-19; living guidelines; molnupiravir; nirmatrelvir/ritonavir; prescribing; remdesivir.

MeSH terms

  • Antiviral Agents / therapeutic use
  • Australia
  • COVID-19*
  • Guideline Adherence
  • Humans
  • South Australia / epidemiology

Substances

  • Antiviral Agents