Severe hypercalcemia as a result of disseminated Candida krusei infection

Int J Infect Dis. 2024 Mar:140:110-112. doi: 10.1016/j.ijid.2024.01.012. Epub 2024 Jan 22.

Abstract

Candida krusei disseminated infection is a rare complication of protracted neutropenia. Herein, we report a case of a 31-year-old male with relapsed acute myeloid leukemia who developed Candida krusei fungemia with cutaneous, ocular, splenic, renal, bone marrow and osseous involvement leading to severe hypercalcemia, treated with parenteral antifungals followed by oral ibrexafungerp.

Keywords: Candida krusei; Hypercalcemia; Invasive candidiasis; Pichia kudriavzevii.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Candidiasis* / complications
  • Candidiasis* / diagnosis
  • Candidiasis* / drug therapy
  • Fungemia*
  • Humans
  • Hypercalcemia* / complications
  • Hypercalcemia* / drug therapy
  • Male
  • Pichia*

Substances

  • Antifungal Agents

Supplementary concepts

  • Pichia kudriavzevii
  • Systemic candidiasis