Mupirocin

Book
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
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Excerpt

Mupirocin belongs to the topical antibiotic class of medications and is utilized for managing and treating various skin and soft tissue infections. Mupirocin was originally developed in the early 1970s and is derived from Pseudomonas fluorescens. Mupirocin is recognized as the most widely used topical antibiotic globally for treating methicillin-resistant Staphylococcus aureus (MRSA), particularly in cases of impetigo. Proper administration of mupirocin effectively eliminates infectious symptoms in over 85% of impetigo cases. Mupirocin has consistently demonstrated its efficacy in eradicating intranasal MRSA colonization in healthcare settings. The topical medication mupirocin received initial approval from the U.S. Food and Drug Administration (FDA) in 1997, and has since been widely prescribed and used globally.

Publication types

  • Study Guide