The Genus Anabasis: A Review on Pharmacological and Phytochemical Properties

Smail Amtaghri; Miloudia Slaoui; Mohamed Eddouks

doi:10.2174/0118715257276051240111060414

The Genus Anabasis: A Review on Pharmacological and Phytochemical Properties

Cardiovasc Hematol Agents Med Chem. 2024 Jan 22. doi: 10.2174/0118715257276051240111060414. Online ahead of print.

Authors

Smail Amtaghri^{1

2}, Miloudia Slaoui², Mohamed Eddouks¹

Affiliations

¹ Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, BP 509, Boutalamine, Errachidia, 52000, Morocco.
² Energy, materials and sustainable development (EMDD) Team- Higher School of Technology-SALE, Center for Water, Natural Resources Environment and Sustainable Development (CERNE2D), Mohammed V University in Rabat, Avenue Ibn Battouta, B.P. 1014, Rabat 10000, Morocco.

PMID: 38258787
DOI: 10.2174/0118715257276051240111060414

Abstract

The genus Anabasis has long been used in phytomedicine. The studied parts of Anabasis species are used as antirheumatic, diuretic, antidotes against poison, anti-erosion, anti-ulcer, and antidiabetic agents, as well as against headache and skin diseases. The objective of the present review was to summarize the phytochemical and pharmacological aspects related to the genus Anabasis. The results of this literature analysis show that among all the species of the Anabasis (A) family, A. aphylla, A. Iranica, A. aretioides, and A. articulata showed antibacterial activity; A. aretioides and A. articulata have antioxidant activity, A. aretioides and A. articulata have antidiabetic activity, A. articulata has cytotoxic activity and A. setifera, A. aretioides, and A. articulata exhibit anti-inflammatory activity. The Anabasis genus contains saponins, and alkaloids, such as anabasine, anabasamine, lupinine, jaxartinine, and triterpenic sapogenins. The study of 15 Anabasis plants has identified 70 compounds with an array of pharmacological activities especially antibacterial, antioxidant, antidiabetic, cytotoxic, and anti-inflammatory activities. However, there is a need for further studies on Anabasis plants before they can be fully used clinically as a potential drug.

Keywords: Anabasis; Anti-diabetic; Anti-inflammatory; Anti-oxidant; Antibacterial; Cytotoxicity; Ethnomedicinal; Medicinal properties; Pharmacology; Phytochemistry.; Toxicology.