New Triphenylphosphonium Salts of Spiropyrans: Synthesis and Photochromic Properties

Molecules. 2024 Jan 11;29(2):368. doi: 10.3390/molecules29020368.

Abstract

The most important area of modern pharmacology is the targeted delivery of drugs, and one of the most promising classes of chemical compounds for creating drugs of this kind are the photochromic spiropyrans, capable of light-controlled biological activity. This work is devoted to the synthesis and study of the photochromic properties of new triphenylphosphonium salts of spiropyrans. It was found that all the synthesized cationic spiropyrans have high photosensitivity, increased resistance to photodegradation and the ability for photoluminescence.

Keywords: luminescent properties; merocyanine; photochromism; photodegradation; spectral–kinetic properties; spiropyran; triphenylphosphonium cation; triphenylphosphonium salts.