Vicarious excretion of 99mTc-pyrophosphate in the gallbladder

Michael Kavanaugh; Hina J Shah

doi:10.1016/j.nuclcard.2024.101814

Vicarious excretion of ^99mTc-pyrophosphate in the gallbladder

J Nucl Cardiol. 2024 May:35:101814. doi: 10.1016/j.nuclcard.2024.101814. Epub 2024 Jan 20.

Authors

Michael Kavanaugh¹, Hina J Shah²

Affiliations

¹ Brigham and Women's Hospital, Department of Radiology, Division of Nuclear Medicine 75 Francis Street Boston 02115, MA, USA. Electronic address: Mkavanaugh1@mgb.org.
² Brigham and Women's Hospital, Department of Radiology, Division of Nuclear Medicine 75 Francis Street Boston 02115, MA, USA; Dana-Farber Cancer Institute, Imaging, 450 Brookline Avenue, Boston 02215, MA, USA. Electronic address: hina_shah@dfci.harvard.edu.

PMID: 38246258
DOI: 10.1016/j.nuclcard.2024.101814

Abstract

Vicarious excretion of tracer and contrast media is a known phenomenon and is not fully understood [1,2]. We report a case of unexpected vicarious excretion of ^99mTc-pyrophosphate in the gallbladder seen on a scan performed to evaluate suspected cardiac amyloidosis, which is the first report of this phenomenon to the best of our knowledge.

Keywords: Amyloid heart disease; Image interpretation; Molecular imaging agents; SPECT; Tracer development.

Publication types

Case Reports

MeSH terms

Aged
Amyloidosis / diagnostic imaging
Cardiomyopathies / diagnostic imaging
Female
Gallbladder* / diagnostic imaging
Humans
Male
Middle Aged
Radiopharmaceuticals* / pharmacokinetics
Technetium Tc 99m Pyrophosphate*

Substances

Technetium Tc 99m Pyrophosphate
Radiopharmaceuticals