1 Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver British Columbia V5Z 1L3, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver British Columbia V6T 1Z4, Canada. Electronic address: adelaidelli@bccrc.ca.
2 Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver British Columbia V5Z 1L3, Canada; Department of Genetics, Ribeirao Preto Medical School, University of Sao Paulo, Sao Paulo, Brazil.
3 Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver British Columbia V5Z 1L3, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver British Columbia V6T 1Z4, Canada. Electronic address: psor@mail.ubc.ca.
In this issue of Molecular Cell, Hofman et al.1 identify the translation of a non-canonical upstream open reading frame of the ASNSD1 gene into a microprotein that supports medulloblastoma growth.