A Case Report: Ovarian Fibrothecoma with Minor Sex Cord Elements

Case Rep Oncol. 2024 Jan 17;17(1):107-112. doi: 10.1159/000534798. eCollection 2024 Jan-Dec.

Abstract

Introduction: Ovarian stromal tumors with minor sex cord elements are rare, and there are not specific imaging features to help in making the diagnosis.

Case presentation: We report a case of this tumor in an 81-year-old woman who was referred to our hospital for constipation and a pelvic mass. Magnetic resonance imaging demonstrated a well-circumscribed mass and isointensity compared to the skeletal muscle on T1-weighted imaging (T1WI) and low signal intensity mixed with high signal ranges on T2-weighted imaging. Dynamic gadolinium-enhanced fat-suppressed T1WI revealed mild and increased enhancement of the peripheral area in the early and delayed phases, respectively. On diffusion-weighted imaging (DWI), a heterogeneously high signal intensity corresponding to the peripheral enhanced area was observed, and the apparent diffusion coefficient values of the high-intensity areas on DWI were low. Malignancy could be suspected, so the mass was surgically removed. Pathological assessment revealed a fibrothecoma with minor sex cord elements.

Conclusion: The tumor's preoperative diagnosis is difficult, although the possibility of this rare tumor from atypical findings on DWI and/or dynamic contrast enhancement studies should be considered.

Keywords: Fibrothecoma; Magnetic resonance imaging; Minor sex cord elements; Ovary.

Publication types

  • Case Reports

Grants and funding

This work was supported by JSPS KAKENHI (Grant No. 22K07757).