Diffuse alveolar hemorrhage from metastatic cardiac angiosarcoma of the lung successfully treated with paclitaxel chemotherapy: A case report and brief literature review

Jieun Yang; Ji Eun Park; Sanghoon Han; Chi Wha Han; Changhwan Kim; Chang Lim Hyun; JeongJae Kim; Jaemin Jo

doi:10.1016/j.rmcr.2021.101538

Diffuse alveolar hemorrhage from metastatic cardiac angiosarcoma of the lung successfully treated with paclitaxel chemotherapy: A case report and brief literature review

Respir Med Case Rep. 2021 Oct 21:34:101538. doi: 10.1016/j.rmcr.2021.101538. eCollection 2021.

Authors

Jieun Yang¹, Ji Eun Park¹, Sanghoon Han¹, Chi Wha Han¹, Changhwan Kim¹, Chang Lim Hyun², JeongJae Kim³, Jaemin Jo¹

Affiliations

¹ Department of Internal Medicine, Jeju National University Hospital, Jeju, Republic of Korea.
² Department of Pathology, Jeju National University Hospital, Jeju, Republic of Korea.
³ Department of Radiology, Jeju National University Hospital, Seoul, Republic of Korea.

Abstract

Diffuse alveolar hemorrhage (DAH) is a life-threatening syndrome caused by various etiologies. DAH has rarely been reported to be associated with metastatic angiosarcoma. However, due to the rarity of complications, it may not be well-recognized by most clinicians. Herein, we report the case of a 70-year-old man with newly diagnosed metastatic cardiac angiosarcoma presenting with DAH. After an immediate bronchoalveolar lavage study and bronchoscopic biopsy, the patient was successfully treated with paclitaxel chemotherapy. Although most patients with this phenomenon have an extremely grave prognosis in previous literature, our experience showed that appropriate evaluation and treatment may be beneficial.

Keywords: Angiosarcoma; Diffuse alveolar hemorrhage; Metastatic; Paclitaxel.

Publication types

Case Reports