Ablation for Single Pulmonary Nodules, Primary or Metastatic. Εndobronchial Ablation Systems or Percutaneous

Paul Zarogoulidis; Vasilis Papadopoulos; Eleni-Isidora Perdikouri; Anastasios Vagionas; Dimitris Matthaios; Aris Ioannidis; Wolfgang Hohemforst-Schmidt; Haidong Huang; Chong Bai; Oikonomou Panagoula; Christina Nikolaou; Charalampos Charalampidis; Christoforos Kosmidis; Konstantinos Sapalidis; Nikolaos Machairiotis; Athanasia Pataka

doi:10.7150/jca.90494

Ablation for Single Pulmonary Nodules, Primary or Metastatic. Εndobronchial Ablation Systems or Percutaneous

J Cancer. 2024 Jan 1;15(4):880-888. doi: 10.7150/jca.90494. eCollection 2024.

Authors

Paul Zarogoulidis¹, Vasilis Papadopoulos², Eleni-Isidora Perdikouri³, Anastasios Vagionas⁴, Dimitris Matthaios⁵, Aris Ioannidis⁶, Wolfgang Hohemforst-Schmidt⁷, Haidong Huang⁸, Chong Bai⁸, Oikonomou Panagoula⁹, Christina Nikolaou⁹, Charalampos Charalampidis¹⁰, Christoforos Kosmidis¹¹, Konstantinos Sapalidis¹¹, Nikolaos Machairiotis¹², Athanasia Pataka¹³

Affiliations

¹ Pulmonary Department, General Clinic Euromedica, Thessaloniki, Greece.
² Oncology Department, University General Hospital of Larissa, Greece.
³ Oncology Department, General Hospital of Volos, Greece.
⁴ Oncology Department, General Hospital of Kavala, Greece.
⁵ Oncology Department, General Hospital of Rhodes, Greece.
⁶ Surgery Department, Genisis Private Clinic, Thessaloniki, Greece.
⁷ Med IV IP, Lung Centre Bamberg Clinics aff. Univ.- of Erlangen, Buger Str. 96049 Bamberg Germany.
⁸ Department of Respiratory and Critical Care Medicine, Changhai Hospital, Navy Military Medical University, Shanghai, 200433, China.
⁹ Surgery Department, Democritus University of Thrace, Alexandroupolis, Greece.
¹⁰ Department of Pathology, University of Cyprus, Cyprus.
¹¹ 3rd University Surgery Department, ``AHEPA`` University Hospital, Thessaloniki, Greece.
¹² Third Department of Obstetrics and Gynecology, University General Hospital "ATTIKON", Medical School of the National and Kapodistrian University of Athens, Athens, Greece.
¹³ Pulmonary Department, G. Papanikolaou General Hospital, Aristotle University of Thessaloniki, Greece.

Abstract

Single pulmonary nodules are a difficult to diagnose imagining artifact. Currently novel diagnostic tools such as Radial-EBUS with or not C-ARM flouroscopy, electromagnetic navigation systems, robotic bronchoscopy and cone beam-compuer tomography (CBCT) can assist in the optimal guidance of biopsy equipment. After diagnosis of lung cancer or metastatic disease as pulmonary nodule, then surgery or ablation methods as local treatment can be applied. The percutaneous ablation systems under computed tomography guidance with radiofrequency, microwave, cryo and thermosphere have been used for several years. In the past 10 years extensive research has been made for endobronchial ablation systems and methods. We will present and comment on the two different ablation methods and present up to date data.

Keywords: Archimedes; CBCT; Cone beam computed tomography; Covidien; Lung Cancer; Medronic; Monarch; NSCLC; ROSE; ablation; biopsy; cryo; microwave; radial-ebus; radiofrequency; thermopshere.