Objective: To analyze the burden of cardiovascular disease (CVD) attributed to low physical activity (LPA) and its changing trends in China from 1990 to 2019. Methods: On the basis of the province results of the Study of Global Burden of Disease 2019 in China, we described the distribution of CVD death and disability-adjusted life year (DALY) attributed to LPA by sex, age and province. Joinpoint 4.9.1.0 was used to calculate the average annual percentage change. Results: In 2019, the number of CVD deaths and DALY attributed to LPA in people aged ≥25 years were 0.127 million and 1.863 million person-years in China, respectively, The age-standardized mortality rate (ASMR) and standardized DALY rate of CVD attributed to LPA were slightly higher in men than in women, and much higher in ischemic heart disease patients than in ischemic stroke patients. The ASMR (8.85/100 000) and the standardized DALY rate (112.34/100 000) of CVD attributed to LPA in China in 2019 showed no obvious change compared with 1990, while decreased in the last decade. The largest increases in the mortality rate and DALY rate were observed in people aged ≥75 years from 1990 to 2019 (26.89%, 15.61%), but the mortality rate and DALY rate in people aged 60-74 years showed a decreasing trend. The mortality rate and DALY rate in men aged 25- 44 years showed the largest increases (37.50%, 35.49%), while women aged ≥75 years had the largest increases (31.00%, 18.02%). In 2019, the highest ASMR and standardized DALY rate of CVD attributed to LPA were found in Jilin, Inner Mongolia and Hebei. The largest increases were found in Qinghai (182.41%, 154.70%), Gansu (181.29%, 152.77%), and Chongqing (132.01%, 102.79%) and the largest decreases were found in Beijing (59.11%, 62.09%), Macau (41.89%, 39.37%) and Guangdong (36.93%, 40.72%) from 1990 to 2019. Conclusion: The disease burden of CVD attributed to LPA in China was quite high and showed gender, age and area specific differences.
目的： 分析1990-2019年中国及各省级行政区人群归因于身体活动不足（LPA）的心血管疾病（CVD）疾病负担及其变化趋势。 方法： 使用2019年全球疾病负担研究中国人群LPA和CVD有关数据，按性别、年龄和省级行政区对归因死亡和伤残调整寿命年（DALY）的分布情况进行描述，采用Joinpoint 4.9.1.0软件计算平均年度变化百分比。 结果： 2019年我国≥25岁人群归因于LPA的CVD死亡人数和DALY分别为12.70万和186.33万人年，年龄标化死亡率（ASMR）和标化DALY率男性略高于女性，缺血性心脏病远高于缺血性脑卒中。与1990年相比，2019年我国LPA导致的CVD ASMR（8.85/10万）和标化DALY率（112.34/10万）基本无变化，而近10年有所下降；≥75岁组的死亡率及DALY率增幅最大（26.89%、15.61%），且死亡率呈上升趋势，而60~74岁组死亡率及DALY率呈下降趋势；男性25~44岁组死亡率和DALY率增幅最大（37.50%、35.49%），女性≥75岁组增幅最大（31.00%、18.02%）。2019年，LPA导致CVD疾病负担最高的省级行政区为吉林、内蒙古和河北。与1990年相比，ASMR、标化DALY率增幅最大的省级行政区为青海（182.41%、154.70%）、甘肃（181.29%、152.77%）和重庆（132.01%、102.79%）；降幅最大的省级行政区为北京（59.11%、62.09%）、澳门（41.89%、39.37%）和广东（36.93%、40.72%）。 结论： 我国归因于LPA的CVD疾病负担仍较重，且存在性别、年龄和地区差异。.