Objectives: To diagnose coronary artery stenosis by using the postmortem computed tomography angiography (PMCTA), and to explore the diagnostic value of PMCTA in sudden cardiac death.
Methods: Six death cases were selected, and the contrast medium iohexol was injected under high pressure through femoral artery approach with 5F pigtail catheter to obtain coronary image data and then the data was analyzed. The results of targeted coronary imaging and coronary artery calcium score (CaS) were compared with the results of conventional autopsy and histopathological examination.
Results: The autopsy and histopathological examination of cases with coronary artery stenosis obtained similar results in targeted coronary angiography, with a diagnostic concordance rate of 83.3%. Targeted coronary angiography could effectively show coronary artery diseases, and the CaS was consistent with the results of conventional autopsy and histopathological examination.
Conclusions: Targeted coronary angiography can be used as an effective auxiliary method for conventional autopsy in cases of sudden cardiac death.
目的: 应用靶向心脏冠状动脉死后计算机体层成像血管造影（postmortem computed tomography angiography，PMCTA）方法对冠状动脉狭窄进行诊断，探索其对冠心病猝死的诊断价值。方法: 选用鉴定实践中的6例死亡案例，用5F猪尾型导管经股动脉入路高压注射对比剂碘海醇，获取冠状动脉影像学数据并处理分析，将冠状动脉靶向显影及冠状动脉钙化积分与常规尸体解剖、组织病理学检验结果进行比较。结果: 尸体解剖和组织病理学检验存在冠状动脉狭窄的病例在靶向心脏冠状动脉造影中均得到相似的结果，诊断吻合率达83.3%。靶向心脏冠状动脉造影方法可以有效显示心脏冠状动脉病变，冠状动脉钙化积分与常规尸体解剖、组织病理学检验结果具有一致性。结论: 靶向心脏冠状动脉造影技术在冠心病猝死案件中可以作为常规尸体检验的有效辅助手段。.
Keywords: 5F pigtail catheter; coronary angiography; coronary artery calcium score (CaS); coronary heart disease; forensic pathology; postmortem computed tomography angiography (PMCTA); sudden death.