[Progress in relationship between long non-coding RNA and myocardial ischemia-reperfusion injury]

Zhonghua Xin Xue Guan Bing Za Zhi. 2024 Jan 24;52(1):96-102. doi: 10.3760/cma.j.cn112148-20231009-00278.
[Article in Chinese]

Abstract

长链非编码RNA（lncRNA）是许多心血管疾病密切相关的信号分子。心肌缺血再灌注损伤（MIRI）的发生与急性心肌梗死、心脏手术等息息相关。近年来发现许多lncRNA在MIRI患者血浆中表达水平有显著变化，推测它们有诊断和治疗MIRI的潜力。该文总结了MIRI的发生机制以及MIRI中25种上调和10种下调的lncRNA的作用机制，为MIRI的早期诊断和治疗提供新思路。.

MeSH terms

  • Apoptosis
  • Humans
  • Myocardial Ischemia*
  • Myocardial Reperfusion Injury* / genetics
  • Myocytes, Cardiac
  • RNA, Long Noncoding* / genetics

Substances

  • RNA, Long Noncoding