Unfavorable efficacy of pembrolizumab for advanced extramammary Paget's disease with high tumor mutation burden after failure of taxane-based regimens

J Dermatol. 2024 Jun;51(6):e203-e204. doi: 10.1111/1346-8138.17101. Epub 2024 Jan 12.
No abstract available

Publication types

  • Letter
  • Case Reports

MeSH terms

  • Aged
  • Antibodies, Monoclonal, Humanized* / administration & dosage
  • Antibodies, Monoclonal, Humanized* / therapeutic use
  • Antineoplastic Agents, Immunological / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Female
  • Humans
  • Male
  • Mutation*
  • Paget Disease, Extramammary* / diagnosis
  • Paget Disease, Extramammary* / drug therapy
  • Paget Disease, Extramammary* / genetics
  • Paget Disease, Extramammary* / pathology
  • Skin Neoplasms / drug therapy
  • Skin Neoplasms / genetics
  • Skin Neoplasms / pathology
  • Taxoids* / administration & dosage
  • Taxoids* / therapeutic use
  • Treatment Failure

Substances

  • Antibodies, Monoclonal, Humanized
  • pembrolizumab
  • Taxoids
  • Antineoplastic Agents, Immunological