Efficacy and safety of microwave ablation and its synergistic potential in the treatment of early-stage non-small cell lung cancer

Xinhang Hu; Qikang Hu; Yu He; Xuyang Yi; Zeyu Wu; Huali Hu; Yifan Ouyang; Fenglei Yu; Muyun Peng

doi:10.1016/j.clinimag.2023.110070

Efficacy and safety of microwave ablation and its synergistic potential in the treatment of early-stage non-small cell lung cancer

Clin Imaging. 2024 Mar:107:110070. doi: 10.1016/j.clinimag.2023.110070. Epub 2024 Jan 5.

Authors

Xinhang Hu¹, Qikang Hu¹, Yu He¹, Xuyang Yi¹, Zeyu Wu¹, Huali Hu¹, Yifan Ouyang¹, Fenglei Yu², Muyun Peng³

Affiliations

¹ Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, China; Hunan Key Laboratory of Early Diagnosis and Precise Treatment of Lung Cancer, The Second Xiangya Hospital of Central South University, Changsha, China.
² Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, China; Hunan Key Laboratory of Early Diagnosis and Precise Treatment of Lung Cancer, The Second Xiangya Hospital of Central South University, Changsha, China. Electronic address: yufenglei@csu.edu.cn.
³ Department of Thoracic Surgery, The Second Xiangya Hospital of Central South University, Changsha, China; Hunan Key Laboratory of Early Diagnosis and Precise Treatment of Lung Cancer, The Second Xiangya Hospital of Central South University, Changsha, China. Electronic address: pengmuyun@csu.deu.cn.

PMID: 38211397
DOI: 10.1016/j.clinimag.2023.110070

Abstract

Lung cancer remains the primary cause of cancer-related mortality globally. In the case of early-stage non-small cell lung cancer (NSCLC), surgical resection, such as lobectomy and sub-lobectomy, continues to be the established standard treatment. However, for patients with insufficient cardiopulmonary function and multiple comorbidities who are unable to undergo surgical resection, nonoperative local therapies, including radiotherapy and thermal ablation, are preferred. In recent years, microwave ablation (MWA) has gained popularity for treating early-stage NSCLC due to its high heating efficiency, good tissue conductance, and heat conduction capabilities. This review provides a comprehensive summary of the current efficacy and safety data regarding MWA for early-stage NSCLC and discusses the potential benefits of combining MWA with other therapies.

Keywords: Early-stage non-small cell lung cancer; Efficacy; Microwave ablation; Safety.

Publication types

Review

MeSH terms

Carcinoma, Non-Small-Cell Lung* / surgery
Catheter Ablation*
Humans
Lung Neoplasms* / surgery
Microwaves / therapeutic use
Radiofrequency Ablation*
Retrospective Studies
Treatment Outcome