How Can Selected Dietary Ingredients Influence the Development and Progression of Endometriosis?

Nutrients. 2024 Jan 2;16(1):154. doi: 10.3390/nu16010154.

Abstract

Endometriosis is a chronic, hormone-dependent disease characterized by the presence of endometrial tissue in ectopic locations. Since the treatment options for this disease are still limited, and the cure rate is unsatisfactory, the search for ways to treat symptoms and modify the course of the disease is of key importance in improving the quality of life of patients with endometriosis. So far, the literature has shown that nutrition can influence endometriosis through hormonal modification and altering the inflammatory or oxidative response. Since the importance of nutrition in this disease is still a subject of scientific research, we aimed to summarize the current knowledge on the role of dietary modifications in endometriosis. Our review showed that nutrients with anti-inflammatory and antioxidant properties, including most vitamins and several trace elements, may influence the pathogenesis of endometriosis and can be considered as the nutrients preventing the development of endometriosis. However, despite the many discoveries described in this review, further interdisciplinary research on this topic seems to be extremely important, as in the future, it may result in the development of personalized therapies supporting the treatment of endometriosis.

Keywords: diet; endometriosis; macronutrients; micronutrients; nutrition; phytoestrogens; vitamins; xenoestrogens.

Publication types

  • Review

MeSH terms

  • Diet
  • Endometriosis*
  • Female
  • Humans
  • Nutrients
  • Nutritional Status
  • Quality of Life