Universal pictures: A lithophane codex helps teenagers with blindness visualize nanoscopic systems

Sci Adv. 2024 Jan 12;10(2):eadj8099. doi: 10.1126/sciadv.adj8099. Epub 2024 Jan 10.

Abstract

People with blindness have limited access to the high-resolution graphical data and imagery of science. Here, a lithophane codex is reported. Its pages display tactile and optical readouts for universal visualization of data by persons with or without eyesight. Prototype codices illustrated microscopy of butterfly chitin-from N-acetylglucosamine monomer to fibril, scale, and whole insect-and were given to high schoolers from the Texas School for the Blind and Visually Impaired. Lithophane graphics of Fischer-Spier esterification reactions and electron micrographs of biological cells were also 3D-printed, along with x-ray structures of proteins (as millimeter-scale 3D models). Students with blindness could visualize (describe, recall, distinguish) these systems-for the first time-at the same resolution as sighted peers (average accuracy = 88%). Tactile visualization occurred alongside laboratory training, synthesis, and mentoring by chemists with blindness, resulting in increased student interest and sense of belonging in science.

MeSH terms

  • Adolescent
  • Blindness*
  • Chitin*
  • Cytoskeleton
  • Electrons
  • Humans
  • Laboratories

Substances

  • Chitin