Interplay between Staphylococcus aureus and the vaginal microbiota

Carla S Maduta; Stephen W Tuffs; John K McCormick; Karine Dufresne

doi:10.1016/j.tim.2023.12.005

Interplay between Staphylococcus aureus and the vaginal microbiota

Trends Microbiol. 2024 Mar;32(3):228-230. doi: 10.1016/j.tim.2023.12.005. Epub 2024 Jan 4.

Authors

Carla S Maduta¹, Stephen W Tuffs², John K McCormick¹, Karine Dufresne³

Affiliations

¹ Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada.
² Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada.
³ Department of Microbiology and Immunology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada. Electronic address: kdufres3@uwo.ca.

PMID: 38182522
DOI: 10.1016/j.tim.2023.12.005

Abstract

Staphylococcus aureus is a proficient colonizer and opportunistic pathogen which can lead to vaginal dysbiosis, aerobic vaginitis, or life-threatening menstrual toxic shock syndrome. Here we explore the complex but underappreciated interactions that S. aureus may impose on the vaginal environment leading to additional disease outcomes.

Keywords: Staphylococcus aureus; aerobic vaginitis; mTSS; menstrual cycle; microbiota; vaginal tract.

MeSH terms

Bacterial Toxins*
Enterotoxins
Female
Humans
Microbiota*
Staphylococcal Infections*
Staphylococcus aureus
Superantigens

Substances

Enterotoxins
Bacterial Toxins
Superantigens