Updates in the Surgical Management of Benign and High-Risk Breast Lesions

Chelsea Marin; Anna Weiss; Jessica C Gooch

doi:10.1016/j.clbc.2023.12.008

Updates in the Surgical Management of Benign and High-Risk Breast Lesions

Clin Breast Cancer. 2023 Dec 21:S1526-8209(23)00312-9. doi: 10.1016/j.clbc.2023.12.008. Online ahead of print.

Authors

Chelsea Marin¹, Anna Weiss², Jessica C Gooch³

Affiliations

¹ Department of Surgery, Division of Surgical Oncology, University of Rochester Medical Center, Rochester, NY.
² Department of Surgery, Division of Surgical Oncology, University of Rochester Medical Center, Rochester, NY; Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY.
³ Department of Surgery, Division of Surgical Oncology, University of Rochester Medical Center, Rochester, NY; Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY. Electronic address: Jessica_Gooch@urmc.rochester.edu.

PMID: 38171944
DOI: 10.1016/j.clbc.2023.12.008

Abstract

Benign breast disease (BBD) is a heterogenous group of lesions often classified as nonproliferative or proliferative, with the latter group further categorized based on the presence of atypia. Although nonproliferative lesions are more common, the risk of breast cancer is elevated in women with proliferative lesions. Historically, the majority of proliferative lesions were excised due to concern for future and/or concomitant breast cancer at the site of the index lesion. However, contemporary data suggest that the risk of cancer associated with various proliferative lesions may be lower than previously thought, and management of BBD has become more nuanced. In this review, we will focus on recent updates in the management of a select group of benign and high-risk lesions.

Keywords: Atypical hyperplasia; Flat epithelial atypia; Lobular carcinoma in situ; Papilloma; Radial scar.

Publication types

Review