Semi-supervised Thyroid Nodule Detection in Ultrasound Videos

IEEE Trans Med Imaging. 2024 Jan 1:PP. doi: 10.1109/TMI.2023.3348949. Online ahead of print.

Abstract

Deep learning techniques have been investigated for the computer-aided diagnosis of thyroid nodules in ultrasound images. However, most existing thyroid nodule detection methods were simply based on static ultrasound images, which cannot well explore spatial and temporal information following the clinical examination process. In this paper, we propose a novel video-based semi-supervised framework for ultrasound thyroid nodule detection. Especially, considering clinical examinations that need to detect thyroid nodules at the ultrasonic probe positions, we first construct an adjacent frame guided detection backbone network by using adjacent supporting reference frames. To further reduce the labour-intensive thyroid nodule annotation in ultrasound videos, we extend the video-based detection in a semi-supervised manner by using both labeled and unlabeled videos. Based on the detection consistency in sequential neighbouring frames, a pseudo label adaptation strategy is proposed for the refinement of unpredicted frames. The proposed framework is validated on 996 transverse viewed and 1088 longitudinal viewed ultrasound videos. Experimental results demonstrated the superior performance of our proposed method in the ultrasound video-based detection of thyroid nodules.