Portal Vein Thrombosis (PVT) Secondary to Protein C Deficiency in a Young Male

Cureus. 2023 Nov 29;15(11):e49688. doi: 10.7759/cureus.49688. eCollection 2023 Nov.

Abstract

A disorder known as portal venous thrombosis (PVT) is characterized by a partial or total obstruction of the portal vein. Although PVT is somewhat uncommon, liver illness is frequently linked to it. Cirrhosis, carcinoma of the liver, myeloproliferative neoplasms, other malignancies, the use of oral contraceptives, intestinal infections, and genetic hypercoagulable illnesses are typical risk factors. In this case report, we discuss the case of a young male patient who had PVT as a result of a protein C deficit. The patient first had abdominal distention due to ascites, and the diagnosis of portal vein thrombosis was later confirmed by a triphasic computed tomography (CT) scan and Doppler ultrasonography. Anticoagulant medications were successfully administered to treat the patient. The importance of identifying PVT in patients with hypercoagulable diseases and the efficacy of anticoagulant therapy in such circumstances are both highlighted by this case.

Keywords: anticoagulant therapy; doppler ultrasound; hypercoagulable disorders; portal vein thrombosis; triphasic ct scan.

Publication types

  • Case Reports