Progress of near-infrared-II fluorescence in precision diagnosis and treatment of colorectal cancer

Yong Wu; Hongtao Cao; Shaoqing Yang; Chaohui Liu; Zhenguo Han

doi:10.1016/j.heliyon.2023.e23209

Progress of near-infrared-II fluorescence in precision diagnosis and treatment of colorectal cancer

Heliyon. 2023 Dec 3;9(12):e23209. doi: 10.1016/j.heliyon.2023.e23209. eCollection 2023 Dec.

Authors

Yong Wu¹, Hongtao Cao¹, Shaoqing Yang¹, Chaohui Liu¹, Zhenguo Han¹

Affiliation

¹ Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China.

Abstract

Colorectal cancer is a malignant tumour with high incidence and mortality worldwide; therefore, improving the early diagnosis of colorectal cancer and implementing a targeted "individualized treatment" strategy is of great concern. NIR-II fluorescence imaging is a large-depth, high-resolution optical bioimaging tool. Around the NIR-II window, researchers have developed a variety of luminescent probes, imaging systems, and treatment methods with colorectal cancer targeting capabilities, which can be visualized and image-guided in clinical surgery. This article aims to overcome the difficulties in diagnosing and treating colorectal cancer. The present review summarizes the latest results on using NIR-II fluorescence for targeted colorectal cancer imaging, expounds on the application prospects of NIR-II optical imaging for colorectal cancer, and discusses the imaging-guided multifunctional diagnosis and treatment platforms.

Keywords: NIR-II; colorectal cancer; precision diagnosis and treatment.

Publication types

Review