The long-term effects of COVID-19 on pulmonary status and quality of life

PeerJ. 2023 Dec 21:11:e16694. doi: 10.7717/peerj.16694. eCollection 2023.

Abstract

Background: Few studies have looked at how SARS-CoV-2 affects pulmonary function, exercise capacity, and health-related quality of life over time. The purpose of this study was to evaluate these characteristics in post COVID-19 subjects 1 year after recovery.

Methods: The study included two groups. The case group included post COVID-19 subjects who had recovered after a year, and the control group included healthy participants who had never tested positive for COVID-19.

Results: The study screened 90 participants, 42 of whom met the eligibility criteria. The findings revealed that the majority of post COVID-19 subjects had relatively normal lung function 1-year post-recovery. A significant reduction in DLCO (B/P%) was observed in the case group vs. control. The exercise capacity test revealed a clinically significant difference in distance walked and a significant difference in the dyspnea post-walk test in the case group compared to the control group. The case group's health-related quality of life domain scores were significantly affected in terms of energy/fatigue, general health, and physical function.

Conclusions: The post COVID-19 subjects were shown to have well-preserved lung function after 1 year. However, some degree of impairment in diffusion capacity, exercise capacity, and health-related quality of life remained.

Keywords: DLCO; Dyspnea; Exercise capacity; PFT; Post-COVID-19; Quality of life; Rehabilitation.

MeSH terms

  • COVID-19* / epidemiology
  • Dyspnea / epidemiology
  • Humans
  • Lung
  • Quality of Life*
  • SARS-CoV-2

Grants and funding

The authors received no funding for this work.