Ag2O-Containing Biocidal Interpolyelectrolyte Complexes on Glass Surfaces-Adhesive Properties of the Coatings

Vladislava A Pigareva; Oleg S Paltsev; Valeria I Marina; Dmitrii A Lukianov; Andrei V Moiseenko; Nikita M Shchelkunov; Andrey A Fedyanin; Andrey V Sybachin

doi:10.3390/polym15244690

Ag₂O-Containing Biocidal Interpolyelectrolyte Complexes on Glass Surfaces-Adhesive Properties of the Coatings

Polymers (Basel). 2023 Dec 13;15(24):4690. doi: 10.3390/polym15244690.

Authors

Vladislava A Pigareva^{1

2}, Oleg S Paltsev¹, Valeria I Marina^{1

3}, Dmitrii A Lukianov^{1

3}, Andrei V Moiseenko⁴, Nikita M Shchelkunov⁵, Andrey A Fedyanin⁵, Andrey V Sybachin¹

Affiliations

¹ Faculty of Chemistry, Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991 Moscow, Russia.
² A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences, Vavilov Street, 28, 119991 Moscow, Russia.
³ Skolkovo Institute of Science and Technology, Center for Molecular and Cellular Biology, Bolshoy Boulevard, 30, 121205 Moscow, Russia.
⁴ Faculty of Biology, Lomonosov Moscow State University, Leninskie Gory, 1-5, 119991 Moscow, Russia.
⁵ Faculty of Physics, Lomonosov Moscow State University, Leninskie Gory, 1-2, 119991 Moscow, Russia.

Abstract

Biocidal coatings are of great interest to the healthcare system. In this work, the biocidal activity of coatings based on a complex biocide containing polymer and inorganic active antibacterial components was studied. Silver oxide was distributed in a matrix of a positively charged interpolyelectrolyte complex (IPEC) of polydiallyldimethylammonium chloride (PDADMAC) and sodium polystyrene sulfonate (PSS) using ultrasonic dispersion, forming nanoparticles with an average size of 5-6 nm. The formed nanoparticles in the matrix are not subject to agglomeration and changes in morphology during storage. It was found that the inclusion of silver oxide in a positively charged IPEC allows a more than 4-fold increase in the effectiveness of the complex biocide against E. coli K12 in comparison with the biocidal effect of PDADMAC and IPEC. Polycation, IPEC, and the IPEC/Ag₂O ternary complex form coatings on the glass surface due to electrostatic adsorption. Adhesive and cohesive forces in the resulting coatings were studied with micron-scale coatings using dynamometry. It was found that the stability of the coating is determined primarily by adhesive interactions. At the macro level, it is not possible to reliably identify the role of IPEC formation in adhesion. On the other hand, use of the optical tweezers method makes it possible to analyze macromolecules at the submicron scale and to evaluate the multiple increase in adhesive forces when forming a coating from IPEC compared to coatings from PDADMAC. Thus, the application of ternary IPEC/Ag₂O complexes makes it possible to obtain coatings with increased antibacterial action and improved adhesive characteristics.

Keywords: adhesion; biocide; coating; functional coating; interfacial complex; interpolyelectrolyte complex; nanoparticles; optical tweezer; polyanion; polycation.

Grants and funding

This work was carried out within the framework of the project “Modern Problems of Chemistry and Physical Chemistry of Macromolecular Compounds” (state budget no. AAAA-A21-121011990022-4).