Bacteremia caused by Comamonas kerstersii in a patient with acute perforated appendicitis and localized peritonitis: case report and literature review

Yingmiao Zhang; Kun Li; Yu Zhan; Lifeng Shi; Yi Zeng; Hui Wang; Zhongxin Lu

doi:10.3389/fmed.2023.1283769

Bacteremia caused by Comamonas kerstersii in a patient with acute perforated appendicitis and localized peritonitis: case report and literature review

Front Med (Lausanne). 2023 Dec 7:10:1283769. doi: 10.3389/fmed.2023.1283769. eCollection 2023.

Authors

Yingmiao Zhang^#¹, Kun Li^#¹, Yu Zhan¹, Lifeng Shi¹, Yi Zeng¹, Hui Wang¹, Zhongxin Lu^{1

2}

Affiliations

¹ Department of Medical Laboratory, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
² Cancer Research Institute of Wuhan, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

^# Contributed equally.

Abstract

Comamonas kerstersii (C. kerstersii) is a Gram-negative bacterium that was initially thought to be non-pathogenic to humans and is abundant in the environment. In recent years, with the availability of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) that enable fast and accurate bacterial identification, there have been increasing number of reports of human infections caused by C. kerstersii, indicating that this organism has emerged as human pathogen. In fact, most clinical isolates of C. kerstersii are recovered from peritoneal liquid, and bacteremia has been infrequently reported. Here, we report a case of bacteremia caused by C. kerstersii in a 28-year-old male patient with acute perforated appendicitis and localized peritonitis and present a comprehensive review of C. kerstersii infections in pathogenic diagnosis and clinical treatment as well as prognosis, thus providing a better understanding of C. kerstersii-related infections.

Keywords: 16S rRNA; Comamonas kerstersii; bacteremia; case report; perforated appendicitis.

Publication types

Case Reports

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by a grant from the Wuhan Municipal Health Commission (Project no. WX21Q42) to YMZ and a local grant from the Central Hospital of Wuhan (grant no. 22YJ57) to KL.