The Travels of Signet-Ring Cell Carcinoma: From Colon to Stomach and Duodenum

Chloe K Tom; Nicholas Placone; Evan Yung; Anisa Shaker

doi:10.14309/crj.0000000000001239

The Travels of Signet-Ring Cell Carcinoma: From Colon to Stomach and Duodenum

ACG Case Rep J. 2023 Dec 21;10(12):e01239. doi: 10.14309/crj.0000000000001239. eCollection 2023 Dec.

Authors

Chloe K Tom¹, Nicholas Placone¹, Evan Yung², Anisa Shaker³

Affiliations

¹ Division of Gastrointestinal and Liver Diseases, University of Southern California, Los Angeles, CA.
² Department of Pathology, University of Southern California, Los Angeles, CA.
³ Division of Gastrointestinal and Liver Diseases and Swallowing and Esophageal Disorders Center, University of Southern California, Los Angeles, CA.

Abstract

Colorectal cancer (CRC) metastasizing to the stomach and duodenum is rare. Even rarer is when the CRC subtype is signet-ring cell carcinoma (SRCC). Endoscopic findings of CRC metastasis to the stomach have been described as solitary and submucosal while duodenal metastasis has been observed to be exophytic. In this report, we describe a case of a middle-aged man with colon SRCC presenting with oral intolerance. He was found to have concurrent metastases to the stomach and duodenum and died 8 months after his SRCC diagnosis.

Keywords: colorectal cancer; esophagogastroduodenoscopy; metastatic cancer; signet-ring cell carcinoma.

Publication types

Case Reports