State-of-the-art electrochemical biosensors based on covalent organic frameworks and their hybrid materials

Shi Jin; Hongxu Chen; Kexuan Pan; Ruyu Li; Xingyu Ma; Rongrong Yuan; Xianshu Meng; Hongming He

doi:10.1016/j.talanta.2023.125557

State-of-the-art electrochemical biosensors based on covalent organic frameworks and their hybrid materials

Talanta. 2024 Apr 1:270:125557. doi: 10.1016/j.talanta.2023.125557. Epub 2023 Dec 16.

Authors

Shi Jin¹, Hongxu Chen², Kexuan Pan³, Ruyu Li⁴, Xingyu Ma⁴, Rongrong Yuan⁵, Xianshu Meng⁶, Hongming He⁷

Affiliations

¹ Department of Basic Science, Jilin Jianzhu University, Changchun, 130118, PR China.
² College of Material and Textile Engineering, Jiaxing University, Jiaxing, 314001, PR China. Electronic address: hx.chen@zjxu.edu.cn.
³ College of Material and Textile Engineering, Jiaxing University, Jiaxing, 314001, PR China.
⁴ Department of Materials Science and Engineering, Jilin Jianzhu University, Changchun, 130118, PR China.
⁵ Department of Materials Science and Engineering, Jilin Jianzhu University, Changchun, 130118, PR China. Electronic address: yuanrongrong@jlju.edu.cn.
⁶ College of Chemistry, Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Tianjin Normal University, Tianjin, 300387, PR China.
⁷ College of Chemistry, Tianjin Key Laboratory of Structure and Performance for Functional Molecules, Tianjin Normal University, Tianjin, 300387, PR China. Electronic address: hxxyhhm@tjnu.edu.cn.

PMID: 38128284
DOI: 10.1016/j.talanta.2023.125557

Abstract

As the development of global population and industry civilization, the accurate and sensitive detection of intended analytes is becoming an important and great challenge in the field of environmental, medical, and public safety. Recently, electrochemical biosensors have been constructed and used in sensing fields, such as antibiotics, pesticides, specific markers of cancer, and so on. Functional materials have been designed and prepared to enhance detection performance. Among all reported materials, covalent organic frameworks (COFs) are emerging as porous crystalline materials to construct electrochemical biosensors, because COFs have many unique advantages, including large surface area, high stability, atom-level designability, and diversity, to achieve a far better sensing performance. In this comprehensive review, we not only summarize state-of-the-art electrochemical biosensors based on COFs and their hybrid materials but also highlight and discuss some typical examples in detail. We finally provide the challenge and future perspective of COFs-based electrochemical biosensors.

Keywords: Biosensor; Covalent organic framework; Electrochemical detection; Hybrid material.

Publication types

Review