A 82-year-old man was admitted to hospital with fever, unresponsiveness, elevated hypersensitive C-reactive protein and neutrophile granulocyte. Ceftriaxone was administrated by intravenous dripping in the emergency room, but the effect was not satisfactory. Following his admission to the ward, cefoperazone sulbactam were given. Elizabethkingia meningoseptica was identified by blood culture and further confirmed by 16S rRNA sequencing. The lumbar puncture showed that cerebrospinal fluid pressure was 80 mmH2O (1 mmH2O=0.0098 kPa) and biochemical results were normal. After 11 days of cefoperazone sulbactam treatment, the patient was discharged with negative blood culture. The hypersensitive C-reactive protein and neutrophile granulocyte had also declined. The patient received levofloxacin tablets for anti-infection treatment for 14 d after discharge. No signs of infection were observed in three months' following up.
一例82岁男性患者因“发热1 d”就诊，主要表现为发热、反应迟钝，外周血超敏C反应蛋白、中性粒细胞百分比明显升高，急诊予头孢曲松静脉滴注抗感染等治疗，效果不佳。收入病房后予头孢哌酮钠舒巴坦钠抗感染治疗，期间血培养发现脑膜脓毒性伊丽莎白金菌，经16S rRNA测序结果确认为脑膜脓毒性伊丽莎白金菌。患者住院期间腰椎穿刺检查脑脊液压为80 mmH2O（1 mmH2O=0.0098 kPa），脑脊液生化检查结果均正常。治疗11 d后血培养阴性，且外周血超敏C反应蛋白、中性粒细胞百分比下降，予以出院。出院后使用左氧氟沙星片继续口服治疗14 d，随访3个月，患者体温正常，无感染症状。.
Keywords: Case report; Cefoperazone sulbactam; Elizabethella spp.; Elizabethkingia meningoseptica; Gene sequencing; Levofloxacin; Septicaemia.