Simultaneous determination of 4-ethylphenol and 4-ethylguaicol on C60 modified dual screen-printed electrochemical sensors

Paula Portugal-Gómez; M Asunción Alonso-Lomillo; Olga Domínguez-Renedo

doi:10.1016/j.talanta.2023.125543

Simultaneous determination of 4-ethylphenol and 4-ethylguaicol on C₆₀ modified dual screen-printed electrochemical sensors

Talanta. 2024 Apr 1:270:125543. doi: 10.1016/j.talanta.2023.125543. Epub 2023 Dec 13.

Authors

Paula Portugal-Gómez¹, M Asunción Alonso-Lomillo¹, Olga Domínguez-Renedo²

Affiliations

¹ Analytical Chemistry Department, Faculty of Sciences, University of Burgos, Pza. Misael Bañuelos s/n, 09001, Burgos, Spain.
² Analytical Chemistry Department, Faculty of Sciences, University of Burgos, Pza. Misael Bañuelos s/n, 09001, Burgos, Spain. Electronic address: olgado@ubu.es.

PMID: 38103285
DOI: 10.1016/j.talanta.2023.125543

Abstract

4-ethylphenol and 4-ethylguaicol levels in wine are associated to organoleptic defects that cause consumer rejection accompanied by significant economic losses for producers. Thus, electrochemical sensors based on screen-printed carbon electrodes (SPCEs) modified with activated fullerene C₆₀ (AC₆₀) have been developed for the analysis of both phenols by direct headspace amperometric measurements. Upon optimization of the experimental variables affecting the sensors performance, the AC₆₀/SPCE sensors presented linearity ranges from 9.9 to 65.4 μg/L and from 19.6 to 107.1 μg/L for 4-ethylphenol and 4-ethylguaicol, respectively. The achieved detection capacities were 10.3 μg/L (4-ethylphenol) and 19.6 μg/L (4-ethylguaicol), with a reproducibility of 6.3 % and 9.1 % (n = 3), respectively. In addition, dual-working AC₆₀/SPCE devices were developed for the simultaneous analysis of both phenols using different working potentials for each electrode. The dual systems were successfully applied in the analysis of different spiked wine samples, obtaining good recoveries ranging from 94 to 108 %.

Keywords: 4-Ethylguaicol; 4-Ethylphenol; Dual screen-printed electrodes; Fullerene C(60); Wine.