A review on versatile applications of biomaterial/polycationic chitosan: An insight into the structure-property relationship

Int J Biol Macromol. 2024 Feb;257(Pt 2):128676. doi: 10.1016/j.ijbiomac.2023.128676. Epub 2023 Dec 12.

Abstract

Chitosan is a versatile and generous biopolymer obtained by alkaline deacetylation of naturally occurring chitin, the second most abundant biopolymer after cellulose. The excellent physicochemical properties of polycationic chitosan are attributed to the presence of varied functional groups such as amino, hydroxyl, and acetamido groups enabling researchers to tailor the structure and properties of chitosan by different methods such as crosslinking, grafting, copolymerization, composites, and molecular imprinting techniques. The prepared derivatives have diverse applications in the food industry, water treatment, cosmetics, pharmaceuticals, agriculture, textiles, and biomedical applications. In this review, numerous applications of chitosan and its derivatives in various fields have been discussed in detail with an insight into their structure-property relationship. This review article concludes and explains the chitosan's biocompatibility and efficiency that has been done so far with future usage and applications as well. Moreover, the possible mechanism of chitosan's activity towards several emerging fields such as energy storage, biodegradable packaging, photocatalysis, biorefinery, and environmental bioremediation are also discussed. Overall, this comprehensive review discusses the science and complete information behind chitosan's wonder function to improve our understanding which is much needful as well as will pave the way towards a sustainable future.

Keywords: Applications; Chitin; Chitosan; Structure-property relationship.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemistry
  • Biodegradation, Environmental
  • Cellulose
  • Chitin / chemistry
  • Chitosan* / chemistry

Substances

  • Chitosan
  • Biocompatible Materials
  • Chitin
  • Cellulose