Bilateral large cell calcifying Sertoli cell tumours: A testicular preservation approach in a young male

Ibrahim A Khalil; Mohamed Hatem; Khaled A Murshed; Majd Alkabbani; Nagy Younes; Khalid Al Rumaihi

doi:10.1016/j.eucr.2023.102628

Bilateral large cell calcifying Sertoli cell tumours: A testicular preservation approach in a young male

Urol Case Rep. 2023 Nov 25:51:102628. doi: 10.1016/j.eucr.2023.102628. eCollection 2023 Nov.

Authors

Ibrahim A Khalil¹, Mohamed Hatem¹, Khaled A Murshed², Majd Alkabbani¹, Nagy Younes¹, Khalid Al Rumaihi¹

Affiliations

¹ Department of Urology, Hamad Medical Corporation, Doha, Qatar.
² Department of Anatomic Pathology, Hamad Medical Corporation, Doha, Qatar.

Abstract

Testicular Large cell calcifying Sertoli cell tumours (LCCSTs) are extremely rare. The primary challenge in benign LCCSTs, which are typically multifocal and bilateral tumours affecting young males, is to confirm the diagnosis to avoid radical intervention and preserve fertility potential. Patient clinical presentation, laboratory results, diagnostic radiological tests along with confirmatory histopathological studies, are the cornerstones in such cases, nevertheless genetic testing is warranted, as LCCSTs can be part of genetic syndrome such Carney complex. We present a case of bilateral benign LCCSTs in young male managed with testicular preservation approach with characteristic clinical, radiological and histopathological features.

Keywords: Carney complex; Large cell calcifying Sertoli cell tumours; Testicular preservation.

Publication types

Case Reports