The impact of environmental cleaning protocol featuring PX-UV in reducing the incidence of multidrug-resistant gram-negative healthcare-associated infection and colonization in intensive care units in Thailand

Supavit Vaivoothpinyo; Ornnicha Sathitakorn; Kittiya Jantarathaneewat; David J Weber; Piyaporn Apisarnthanarak; Sasinuch Rutjanawech; Pichaya Tantiyavarong; Anucha Apisarnthanarak

doi:10.1017/ice.2023.255

The impact of environmental cleaning protocol featuring PX-UV in reducing the incidence of multidrug-resistant gram-negative healthcare-associated infection and colonization in intensive care units in Thailand

Infect Control Hosp Epidemiol. 2024 May;45(5):684-687. doi: 10.1017/ice.2023.255. Epub 2023 Dec 13.

Authors

Supavit Vaivoothpinyo¹, Ornnicha Sathitakorn¹, Kittiya Jantarathaneewat^{2

3}, David J Weber⁴, Piyaporn Apisarnthanarak⁵, Sasinuch Rutjanawech^{1

3}, Pichaya Tantiyavarong⁶, Anucha Apisarnthanarak^{1

3}

Affiliations

¹ Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand.
² Department of Pharmaceutical Care, Faculty of Pharmacy, Thammasat University, Pathum Thani, Thailand.
³ Research Group in Infectious Diseases Epidemiology and Prevention, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand.
⁴ University of North Carolina, Gillings School of Global Public Health, Chapel Hill, North Carolina, United States.
⁵ Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
⁶ Department of Clinical Epidemiology, Faculty of Medicine, Thammasat University, Pathum Thani, Thailand.

PMID: 38088177
DOI: 10.1017/ice.2023.255

Abstract

In this quasi-experimental study, implementing PX-UV to the standard environmental cleaning protocol was associated with a reduction in the overall incidence of multidrug-resistant (MDR) gram-negative organisms (P = .01) and MDR Acinetobacter baumannii (P = .001) in intervention intensive care units. However, the intervention did not reduce patient length of stay and 30-day mortality.

MeSH terms

Acinetobacter Infections* / drug therapy
Acinetobacter baumannii*
Anti-Bacterial Agents / therapeutic use
Cross Infection* / epidemiology
Delivery of Health Care
Drug Resistance, Multiple, Bacterial
Humans
Incidence
Intensive Care Units
Thailand / epidemiology

Substances

Anti-Bacterial Agents