Associated Risk Factors for Extended Operative Time Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database

Paul Serrato; Astrid C Hengartner; Sumaiya Sayeed; Alexandre J Prassinos; Michael Alperovich; Michael DiLuna; Aladine A Elsamadicy

doi:10.1097/SCS.0000000000009920

Associated Risk Factors for Extended Operative Time Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database

J Craniofac Surg. 2023 Dec 11. doi: 10.1097/SCS.0000000000009920. Online ahead of print.

Authors

Paul Serrato¹, Astrid C Hengartner¹, Sumaiya Sayeed¹, Alexandre J Prassinos², Michael Alperovich², Michael DiLuna¹, Aladine A Elsamadicy¹

Affiliations

¹ Department of Neurosurgery, Yale University School of Medicine.
² Department of Plastic and Reconstructive Surgery, Yale University School of Medicine, New Haven, CT.

PMID: 38078913
DOI: 10.1097/SCS.0000000000009920

Abstract

Study design: Retrospective cohort study.

Objectives: The aim of this study was to identify the factors associated with extended operative time (EOT) for pediatric patients with craniosynostosis undergoing cranial vault remodeling (CVR).

Methods: A retrospective cohort study was performed using the 2012 to 2021 American College of Surgeons National Surgical Quality Improvement Program Pediatric--Pediatric database. Pediatric patients below 2 years old with craniosynostosis who underwent CVR were identified using Current Procedural Terminology and International Classification of Diseases-9/10 codes. Patients were dichotomized according to whether they encountered an EOT, which was defined as operative time greater than the 75th percentile for the entire cohort (246 min). Patient demographics, comorbidities, intraoperative variables, postoperative adverse events, and health care resource utilization were assessed. Multivariate logistic regression analysis was utilized to identify predictors of EOT and length of stay.

Results: In the cohort of 9817 patients undergoing CVR, 24.3% experienced EOT. The EOT cohort was significantly older and less likely to be non-Hispanic White. Patient comorbidities and surgical adverse events were more frequent among the EOT cohort, including proportions of postoperative surgical site infections. Independent predictors for EOT included age, racial identity, weight, and a higher American Society of Anesthesiologists classification. EOT was found to be an independent predictor for prolonged hospitalization EOT [adjusted odds ratios: 0.78 (0.44-1.13), P<0.001].

Conclusions: This study demonstrates that age, race, and comorbidities contribute to EOT after CVR for craniosynostosis. EOT is independently associated with a longer length of stay. Additional investigations to further understand the risk factors and impacts of extended EOT are warranted to improve patient outcomes.