A unique case of glaucoma associated with heterotopic bone formation in the anterior chamber angle

Rodolfo Bonatti; Bonnie He; Sylvia Pasternak; Brennan D Eadie

doi:10.1016/j.ajoc.2023.101959

A unique case of glaucoma associated with heterotopic bone formation in the anterior chamber angle

Am J Ophthalmol Case Rep. 2023 Nov 10:32:101959. doi: 10.1016/j.ajoc.2023.101959. eCollection 2023 Dec.

Authors

Rodolfo Bonatti^{1

2}, Bonnie He^{1

2}, Sylvia Pasternak^{1

2

3

4}, Brennan D Eadie^{1

2}

Affiliations

¹ Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
² Department of Ophthalmology and Visual Sciences, Dalhousie University, Halifax, Nova Scotia, Canada.
³ Department of Pathology and Laboratory Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
⁴ Department of Medicine, Division of Dermatology, Dalhousie University, Halifax, Nova Scotia, Canada.

Abstract

Purpose: To describe a unique case of unilateral open angle glaucoma secondary to heterotopic bone formation in the anterior chamber angle.

Observations: A 57 year-old male with an unremarkable history presented with right eye pain. Anterior segment examination demonstrated a solid, white deposit overlying the trabecular meshwork and peripheral iris associated with an intraocular pressure of 44 mmHg. The left eye examination was unremarkable. Biopsy of the material surprisingly showed heterotopic bone. Removal of the material and medical treatment were unable to adequately control the intraocular pressure and a trabeculectomy was successfully performed.

Conclusions and importance: This case demonstrates a unique cause of secondary open angle glaucoma: heterotopic bone formation in the anterior chamber angle.

Keywords: Anterior chamber angle; Bone; Glaucoma; Open angle; Trabeculectomy.

Publication types

Case Reports