Allogenic Bone Graft in Dentistry: A Review of Current Trends and Developments

Int J Mol Sci. 2023 Nov 22;24(23):16598. doi: 10.3390/ijms242316598.

Abstract

In an effort to prepare non-autologous bone graft or biomaterial that would possess characteristics comparable to autologous bone, many different allogenic bone derivatives have been created. Although different existing processing methods aim to achieve the very same results, the specific parameters applied during different stages material preparation can result in significant differences in the material's mechanical and biological properties The properties, including osteoconductive, osteoinductive, and even osteogenic potential, can differ vastly depending on particular preparation and storage techniques used. Osteogenic properties, which have long been thought to be characteristic to autogenic bone grafts only, now seem to also be achievable in allogenic materials due to the possibility to seed the host's stem cells on a graft before its implantation. In this article, we aim to review the available literature on allogenic bone and its derivatives as well as the influence of different preparation methods on its performance.

Keywords: allograft; bone; dentistry; derivatives; osteogenic; osteoinductive; properties.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials*
  • Bone Regeneration
  • Bone Transplantation / methods
  • Bone and Bones*
  • Dentistry
  • Osteogenesis

Substances

  • Biocompatible Materials