Rational design of a rapidly responsive and highly selective fluorescent probe for SO2 derivatives detection and imaging

Shiyi Zhang; Xiaopeng Yang; Ying Xu; Haiyang Wang; Fei Luo; Guangming Fu; Dingwei Yan; Miao Lai; Yu Ke; Yong Ye; Xiaoming Ji

doi:10.1016/j.foodchem.2023.138151

Rational design of a rapidly responsive and highly selective fluorescent probe for SO₂ derivatives detection and imaging

Food Chem. 2024 May 1:439:138151. doi: 10.1016/j.foodchem.2023.138151. Epub 2023 Dec 6.

Authors

Shiyi Zhang¹, Xiaopeng Yang², Ying Xu³, Haiyang Wang¹, Fei Luo¹, Guangming Fu¹, Dingwei Yan¹, Miao Lai¹, Yu Ke⁴, Yong Ye⁵, Xiaoming Ji⁶

Affiliations

¹ College of Tobacco Science, Henan Agricultural University, Zhengzhou 450046, China.
² College of Tobacco Science, Henan Agricultural University, Zhengzhou 450046, China. Electronic address: xiaopengyang@henau.edu.cn.
³ School of Pharmaceutical Sciences, and Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou University, Zhengzhou 450001, China.
⁴ School of Pharmaceutical Sciences, and Collaborative Innovation Center of New Drug Research and Safety Evaluation, Zhengzhou University, Zhengzhou 450001, China. Electronic address: ky@zzu.edu.cn.
⁵ Green Catalysis Center, and College of Chemistry, Zhengzhou University, Zhengzhou 450001, China.
⁶ College of Tobacco Science, Henan Agricultural University, Zhengzhou 450046, China. Electronic address: xiaomingji@henau.edu.cn.

PMID: 38064833
DOI: 10.1016/j.foodchem.2023.138151

Abstract

Sulfur dioxide (SO₂) is emerging as a double-edged molecule, while plays vital roles in food and biological system. However, the fast, highly sensitive, and versatile fluorescent probe still remains a tough challenge among current reports. Herein, we developed a novel aggregation-induced emission (AIE) fluorescent probe TPE-PN for specifically sensing SO₂ derivatives with high sensitivity (150 nmol/L) and rapid response time (10 s) based on intramolecular charge transfer (ICT) mechanism. And the fluorescence at 575 nm decreased tremendously with 31-fold after the probe was treated with HSO₃^-. Employing the probe, the accurate analysis of HSO₃^- was successfully realized in food samples, cells, plant tissues, and zebrafishes. Furthermore, we successfully demonstrate the eruption of SO₂ derivatives within plant during drought and salt stress processes. Therefore, probe TPE-PN illustrates significant potential for applications in food analysis and monitoring of SO₂ derivatives levels in biological systems under stress conditions.

Keywords: Detection; Fluorescent probe; Imaging; SO(2); Stress.

MeSH terms

Fluorescence
Fluorescent Dyes*
HeLa Cells
Humans
Mitochondria* / chemistry
Sulfur Dioxide / analysis

Substances

Fluorescent Dyes
Sulfur Dioxide