Effectiveness of Distal Sodium Channel Block in Managing Lumbosacral Radicular Syndrome: A Pilot Study

J Coll Physicians Surg Pak. 2023 Dec;33(12):1449-1453. doi: 10.29271/jcpsp.2023.12.1449.

Abstract

Objective: To find the effectiveness of distal sodium channel blocks in managing lumbosacral radicular syndrome.

Study design: Open-labelled, non-randomised, single-group, prospective, pilot study. Place and Duration of the Study: Pain Clinic of Armed Forces Institute of Rehabilitation Medicine (AFIRM) Rawalpindi, Pakistan, from January to June 2022.

Methodology: Patients having low back pain radiating to L5/S1/both dermatomes with severity of numerical rating scale (NRS) score of more than 4/10 were included. Straight leg raise (SLR) and NRS score were noted down at baseline and at 30 minutes, 24 hours, 1 week, and 4 weeks post-distal sodium channel block (DSCB). DSCB was performed at beta 1, 2, 3, and 5 portals using 2 ml of 2% injection plain lignocaine + 1 ml (40 mg) injection triamcinolone + 7 ml distilled water. Statistical analysis was done using Statistical Package for Social Sciences (SPSS) 21.

Results: Out of 50 patients, 24 (48%) were females and 26 (52%) were males. No serious procedural complications were noted. Post-DSCB, follow-up was done for 4 weeks. A significant fall in NRS and an increase in SLR score were observed at every visit. Results were statistically significant (p<0.001) when mean NRS and SLR scores at every follow-up were compared for pre- and post-DSCBs.

Conclusion: DSCB reduced pain and improved SLR in patients even at 4 weeks of follow-up. Advantages included immediate pain relief, easy to perform as outdoor procedure, cost-effective and a time buying alternative procedure allowing for the analgesic effect of medicine to kick in.

Key words: Radiculopathy, Low-back pain, Epidural spinal injection, Sciatica, Pain management, Distal sodium channel blocks.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Female
  • Humans
  • Low Back Pain* / drug therapy
  • Low Back Pain* / etiology
  • Male
  • Pain Management / adverse effects
  • Pain Management / methods
  • Pilot Projects
  • Prospective Studies
  • Radiculopathy* / complications
  • Radiculopathy* / drug therapy
  • Treatment Outcome