Sentinel lymph node mapping in endometrial cancer: Current evidence and practice

J Surg Oncol. 2024 Jan;129(1):117-119. doi: 10.1002/jso.27550. Epub 2023 Dec 7.

Abstract

Surgical staging with total hysterectomy, bilateral salpingo-oophorectomy, and lymph node assessment is the standard of care for patients with clinical early-stage endometrial cancer. Traditionally, complete pelvic and para-aortic lymphadenectomy (LND) was performed to assess for nodal metastases; however, numerous prospective studies have demonstrated that sentinel lymph node biopsy has similar diagnostic accuracy, and is an acceptable alternative to complete LND. This has led to a paradigm shift in endometrial cancer staging.

Keywords: endometrial cancer; high-grade; sentinel lymph node; staging.

Publication types

  • Review

MeSH terms

  • Endometrial Neoplasms* / pathology
  • Female
  • Humans
  • Lymph Node Excision
  • Lymph Nodes / pathology
  • Lymph Nodes / surgery
  • Neoplasm Staging
  • Prospective Studies
  • Sentinel Lymph Node Biopsy
  • Sentinel Lymph Node* / pathology
  • Sentinel Lymph Node* / surgery