Examining the disparities of anti-malarial drug consumption among children under the age of five: a study of 5 malaria-endemic countries

Malar J. 2023 Dec 5;22(1):370. doi: 10.1186/s12936-023-04805-x.

Abstract

Background: Malaria is one of the most prominent illnesses affecting children, ranking as one of the key development concerns for many low- and middle-income countries (LMICs). There is not much information available on the use of anti-malarial drugs in LMICs in children under five. The study aimed to investigate disparities in anti-malarial drug consumption for malaria among children under the age of five in LMICs.

Methods: This study used recent available cross-sectional data from the Malaria Indicator Survey (MIS) datasets across five LMICs (Guinea, Kenya, Mali, Nigeria, and Sierra Leone), which covered a portion of sub-Saharan Africa. The study was carried out between January 2, 2023, and April 15, 2023, and included children under the age of five who had taken an anti-malarial drug for malaria 2 weeks before the survey date. The outcome variable was anti-malarial drug consumption, which was classified into two groups: those who had taken anti-malarial drugs and those who had not.

Results: In the study of LMICs, 32,397 children under five were observed, and among them, 44.1% had received anti-malarial drugs. Of the five LMICs, Kenya had the lowest (9.2%) and Mali had the highest (70.5%) percentages of anti-malarial drug consumption. Children under five with malaria are more likely to receive anti-malarial drugs if they are over 1 year old, live in rural areas, have mothers with higher education levels, and come from wealthier families.

Conclusion: The study emphasizes the importance of developing universal coverage strategies for anti-malarial drug consumption at both the national and local levels. The study also recommends that improving availability and access to anti-malarial drugs may be necessary, as the consumption of these drugs for treating malaria in children under the age of five is shockingly low in some LMICs.

Keywords: Antimalarial drug consumption; Children under five; LMICs; MIS; Malaria.

MeSH terms

  • Antimalarials* / therapeutic use
  • Child
  • Cross-Sectional Studies
  • Female
  • Humans
  • Infant
  • Kenya
  • Malaria* / drug therapy
  • Malaria* / epidemiology
  • Mothers

Substances

  • Antimalarials