IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion

Hirohito Sugawara; Tomokazu Takahashi; Yukishige Kimura; Azumi Matsui; Tamaki Matsumoto; Kimio Nishisato; Mitsuhiro Nishimura

doi:10.1155/2023/9223342

IgG4-Related Pericarditis Diagnosed by Accumulated Pericardial Effusion

Case Rep Cardiol. 2023 Nov 24:2023:9223342. doi: 10.1155/2023/9223342. eCollection 2023.

Authors

Hirohito Sugawara^{1

2}, Tomokazu Takahashi¹, Yukishige Kimura¹, Azumi Matsui¹, Tamaki Matsumoto¹, Kimio Nishisato¹, Mitsuhiro Nishimura¹

Affiliations

¹ Department of Cardiology, Tenshi Hospital, 1-1 North-12 East-3, Higashi-ku, Sapporo, Hokkaido, Japan 0658611.
² Division of Nephrology, Department of Internal Medicine, Showa University Northern Yokohama Hospital, 35-1, Chigasakichuo, Tsuzuki-ku, Yokohama, Japan 2248503.

Abstract

IgG4-related pericarditis has rarely been reported. Here, we report a case of IgG4-related disease that presented with pericardial effusion. A 67-year-old female who presented with palpitations and chest pain was admitted because of a large amount of pericardial effusion that required drainage. The patient underwent pericardial drainage, and the symptoms were gradually alleviated. IgG4 levels were elevated in the serum and pericardial effusions. A biopsy specimen of ¹⁸F-FDG accumulated in the submandibular gland showed lymphocyte infiltration with IgG4-positive cells. The patient was diagnosed with IgG4-related pericarditis. Glucocorticoids resolved serological and imaging abnormalities. Prompt treatment improves the disease status.

Publication types

Case Reports