Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Treated with Radiation Therapy: A Case Report and Review of the Literature

Case Rep Oncol. 2023 Dec 1;16(1):1528-1535. doi: 10.1159/000534802. eCollection 2023 Jan-Dec.

Abstract

Introduction: Mucosa-associated lymphoid tissue lymphoma (MALT lymphoma or MALToma) is a prevalent type of primary pulmonary lymphoma. Typically, the primary therapeutic approaches involve surgery or chemotherapy, although there have been instances of radiation therapy being employed.

Case report: We present a case of pulmonary MALToma that exhibited progression despite rituximab therapy. Subsequently, the patient demonstrated a positive response to radiation therapy.

Conclusion: This case highlights the potential efficacy of radiation therapy as a treatment option for pulmonary MALToma, especially in cases where other conventional treatments like rituximab have proven ineffective. Further research and studies are warranted to better understand the role of radiation therapy in managing pulmonary MALToma and to determine optimal treatment strategies for patients with this condition.

Keywords: Case report; Mucosa-associated lymphoid tissue lymphoma; Pulmonary mucosa-associated lymphoid tissue lymphoma; Radiation therapy.

Publication types

  • Case Reports

Grants and funding

No funding was received during this case study.